Yukio Nakamura Selected Research

eldecalcitol (ED 71)

1/2022	Efficacy of romosozumab for osteoporosis in a patient with osteogenesis imperfecta: A case report.
12/2019	Effects of monthly minodronate with or without eldecalcitol addition in osteoporosis patients with rheumatoid arthritis: An 18-month prospective study.
6/2019	Additive effects of eldecalcitol in poorly responding long-term bisphosphonate treatment for osteoporosis.
3/2018	Comparison of the effects of denosumab with either active vitamin D or native vitamin D on bone mineral density and bone turnover markers in postmenopausal osteoporosis.
3/2017	Comparison of effectiveness and safety of ibandronate and minodronate combined with eldecalcitol in primary osteoporosis of women: A 1-year follow-up study.
12/2015	Eldecalcitol, in Combination with Bisphosphonate, Is Effective for Treatment of Japanese Osteoporotic Patients.

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Yukio Nakamura Research Topics

Disease

45	Osteoporosis 01/2023 - 01/2015
33	Neoplasms (Cancer) 03/2024 - 08/2002
19	Thalassemia 01/2022 - 01/2016
18	Hemoglobinopathies 01/2024 - 01/2016
16	Sickle Cell Anemia (Hemoglobin S Disease) 12/2023 - 01/2016
12	Bone Resorption 01/2022 - 08/2015
10	Rheumatoid Arthritis 01/2023 - 04/2017
8	Postmenopausal Osteoporosis 01/2022 - 11/2012
7	Hepatocellular Carcinoma (Hepatoma) 03/2024 - 08/2011
7	Anemia 01/2022 - 11/2005
6	Pain (Aches) 08/2023 - 01/2004
6	Stomach Neoplasms (Stomach Cancer) 10/2017 - 01/2007
5	Inflammation (Inflammations) 10/2023 - 08/2005
5	Breast Neoplasms (Breast Cancer) 01/2018 - 11/2010
5	Liver Diseases (Liver Disease) 12/2014 - 08/2011
5	Neoplasm Metastasis (Metastasis) 11/2014 - 01/2008
4	Osteogenesis Imperfecta (Lobstein Disease) 01/2022 - 01/2017
4	Body Weight (Weight, Body) 01/2020 - 07/2005
3	Colorectal Neoplasms (Colorectal Cancer) 12/2015 - 04/2010
3	Squamous Cell Carcinoma of Head and Neck 11/2010 - 07/2008
3	Smear Layer 02/2008 - 04/2005
2	Osteoporotic Fractures 03/2023 - 01/2020
2	Diamond-Blackfan Anemia (Anemia, Diamond Blackfan) 05/2022 - 01/2022
2	Arthritis (Polyarthritis) 01/2022 - 08/2005
2	beta-Thalassemia (Cooley's Anemia) 01/2022 - 01/2021
2	Sideroblastic Anemia 01/2022 - 11/2014
2	Ehlers-Danlos Syndrome (Syndrome, Ehlers-Danlos) 01/2022 - 01/2021
2	Chronic Disease (Chronic Diseases) 01/2022 - 01/2018
2	Inborn Genetic Diseases (Disease, Hereditary) 01/2021 - 10/2020
2	Hypoxia (Hypoxemia) 01/2021 - 02/2005
2	Lung Neoplasms (Lung Cancer) 11/2019 - 01/2011
2	Hypocalcemia 01/2018 - 01/2017
2	Carcinogenesis 10/2017 - 11/2016
2	Leukemia 10/2017 - 01/2009
2	Infections 01/2017 - 08/2009
2	Kyphosis 11/2016 - 01/2016
2	Fibrosis (Cirrhosis) 01/2014 - 06/2013
2	Liver Failure 01/2014 - 03/2012
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2013 - 02/2005
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2012 - 05/2011

Drug/Important Bio-Agent (IBA)

32	Denosumab FDA Link 01/2023 - 12/2015
25	GlobinsIBA 01/2024 - 01/2016
14	Diphosphonates (Bisphosphonates)IBA 09/2019 - 11/2012
11	Fetal Hemoglobin (Hemoglobin F)IBA 06/2023 - 01/2018
11	Vitamin D FDA LinkGeneric 01/2022 - 12/2015
10	Proteins (Proteins, Gene)FDA Link 11/2023 - 10/2007
6	romosozumabIBA 01/2023 - 01/2021
6	eldecalcitol (ED 71)IBA 01/2022 - 12/2015
6	CalciumIBA 01/2022 - 01/2017
6	Hemoglobins (Hemoglobin)IBA 01/2021 - 01/2016
5	Ibandronic Acid (Boniva)FDA Link 01/2022 - 01/2017
4	GlucocorticoidsIBA 01/2023 - 03/2018
4	Alendronate (Alendronate Sodium)FDA LinkGeneric 01/2022 - 11/2012
4	Erythropoietin FDA Link 01/2022 - 06/2003
4	Collagen Type I (Type I Collagen)IBA 06/2019 - 12/2015
4	Angiotensin IIIBA 11/2008 - 07/2005
3	CytokinesIBA 01/2023 - 03/2012
3	Transcription Factors (Transcription Factor)IBA 01/2023 - 01/2015
3	Messenger RNA (mRNA)IBA 01/2021 - 04/2008
3	Tartrate-Resistant Acid PhosphataseIBA 01/2021 - 12/2015
3	ORALIT (ORS)IBA 01/2021 - 01/2016
3	YM 529IBA 12/2019 - 09/2016
3	Alkaline PhosphataseIBA 06/2019 - 01/2016
3	alfacalcidolIBA 03/2018 - 12/2015
3	goniothalaminIBA 01/2017 - 10/2015
3	LigandsIBA 01/2017 - 10/2009
2	Peptides (Polypeptides)IBA 11/2023 - 04/2008
2	Bovine Serum AlbuminIBA 11/2023 - 01/2013
2	Immune Checkpoint InhibitorsIBA 01/2023 - 01/2020
2	AntigensIBA 01/2023 - 08/2005
2	Ribosomal Proteins (Ribosomal Protein)IBA 05/2022 - 01/2022
2	RNA (Ribonucleic Acid)IBA 05/2022 - 01/2021
2	Zoledronic Acid (Zometa)FDA Link 11/2021 - 01/2020
2	HomocysteineIBA 11/2021 - 08/2002
2	Parathyroid Hormone (Parathormone)IBA 01/2021 - 12/2015
2	hydroxide ionIBA 01/2021 - 01/2017
2	ChromatinIBA 01/2021 - 04/2011
2	pentosidineIBA 01/2021 - 01/2015
2	Indicators and Reagents (Reagents)IBA 10/2020 - 08/2011
2	CateninsIBA 11/2019 - 01/2016
2	Teriparatide (Parathar)FDA Link 07/2019 - 01/2017
2	Estrogens (Estrogen)FDA Link 01/2019 - 01/2018
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2018 - 01/2018
2	Long Noncoding RNAIBA 01/2018 - 10/2017
2	Untranslated RNA (Noncoding RNA)IBA 10/2017 - 06/2016
2	Risedronic Acid (Actonel)FDA LinkGeneric 09/2016 - 11/2012
2	Insulin (Novolin)FDA Link 06/2016 - 01/2015
2	DNA (Deoxyribonucleic Acid)IBA 01/2016 - 05/2005
2	Biomarkers (Surrogate Marker)IBA 12/2015 - 01/2011
2	AcidsIBA 11/2014 - 02/2008
2	telomerase RNA (bTR)IBA 08/2011 - 08/2011

Therapy/Procedure

42	Therapeutics 05/2024 - 06/2003
8	Drug Therapy (Chemotherapy) 02/2012 - 01/2007
7	Hepatectomy 01/2014 - 01/2011
6	Transplantation 01/2022 - 01/2004
3	Solid-State Lasers 12/2006 - 01/2002
2	Knee Replacement Arthroplasty (Total Knee Replacement) 01/2024 - 01/2003
2	Conservative Treatment 01/2016 - 01/2014
2	Liver Transplantation 01/2014 - 01/2012
2	Radiotherapy 06/2012 - 05/2011